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Title (english): Capability of detection - Part 5: Methodology in the linear and non-linear calibration cases (ISO 11843-5:2008); Text in German and English

Document type: Standard

Publication date: 2010-08

Overview:

The standard DIN ISO 11843-5 describes basic methods to a) construct a precision profile for the response variable, namely a description of the standard deviation or coefficient of variation of the response variable as a function of the net state variable, b) transform this precision profile into a precision profile for the net state variable in conjunction with the calibration function, and c) use the latter precision profile to estimate the critical value and minimum detectable value of the net state variable. The described methods are useful for checking the detection of a certain substance by various types of measurement equipment. Included are the detection of persistent organic pollutants in the environment, such as dioxins, pesticides and hormone-like chemicals, by competitive ELISA (enzyme-linked immunosorbent assay), and tests of bacterial endotoxins that induce hyperthermia in humans. The standard applies to all sectors. The Committee responsible for this standard is NA 147-00-02 AA "Angewandte Statistik" ("Applied statistics") at DIN.

Language: German, English

Document: references